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Reports that antibody levels are low in one-third of those who have recovered from a new type of coronavirus infection


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Reports that antibody levels are low in one-third of those who have recovered from a new type of coronavirus infection

Researchers at Fudan University in China have found that among those who have recovered from a new type of coronavirus infection (COVID-19), some have low levels of the new type of coronavirus (SARS-CoV-2) antibody. It has been reported. The dissertation was not peer-reviewed and should not be used as a clinical guideline, but the content may affect future vaccine development.

Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications
https://doi.org/10.1101/2020.03.30.20047365


Coronavirus: low antibody levels raise questions about reinfection risk | South China Morning Post
https://www.scmp.com/news/china/science/article/3078840/coronavirus-low-antibody-levels-raise-questions-about

The plasma of a person who has recovered from the disease contains antibodies to the virus and has been used to treat the "Spanish cold" during the 1918 flu and Ebola.

Similarly, for those who have recovered from the new coronavirus infection,plasmaIs thought to contain antibodies to the new coronavirus,Clinical trials are underway.

However, according to a research team at Fudan University, analysis of blood samples from 175 patients discharged from the Shanghai Public Health Clinical Center showed that antibody levels were unexpectedly low in nearly one-third of patients. He understood that. Ten of them reported low antibody levels that could not be detected in the lab.

The subjects of the survey were all those who had just recovered from mild symptoms. This is because many patients in the intensive care unit already had antibodies. Studies showed that antibody levels increased with age, with patients aged 60 to 85 having more than three times the amount of antibodies as patients aged 15 to 39.

The research team says, "These individuals are at increased risk of reinfection and need to be investigated in further studies."

With this new coronavirus, it has been reported that those who once recovered from infectious disease have been re-infected, and it seems likely they will need to be prepared to face the problem for a long time.

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